June 24, 2023

UC symptom: Fatigue

Some resources on fatigue. Fatigue/brain fog has been more prominent for me in the last year. Mostly related to nutritional deficiencies i.e. iron, but auto immune conditions can cause fatigue even in between flare ups.

 
1. https://www.medicalnewstoday.com/articles/ulcerative-colitis-and-fatigue-whats-the-link#how-can-ulcerative-colitis-cause-fatigue
"Several aspects of ulcerative colitis can cause fatigue. For example, the Crohn’s and Colitis Foundation indicates that IBD can lead to fatigue because of:
arthritis, which is a common co-occurring condition with ulcerative colitis
- inflammation
- anemia
- poor sleep
- nutritional deficiencies
- medication side effects
Fatigue is a common effect of these factors.
People with ulcerative colitis often have folate or vitamin B12 deficiencies.
Several medications to treat IBD — including AZA, 6-MP, methotrexate, antidepressants, narcotics, and steroids — can also cause fatigue."

2. "Fatigue in Inflammatory Bowel Diseases: Etiologies and Management"

"... looked at some of the potential causes of fatigue in people with IBD. The researchers noted some additional causes, including:

changes in the gut microbiome
psychological conditions, such as depression
complications from active disease
persistence of active disease"

3. "Psychological distress, iron deficiency, active disease and female gender are independent risk factors for fatigue in patients with ulcerative colitis"

"Another study, this time from 2018, noted that females with ulcerative have a higher risk of experiencing fatigue. The researchers also noted that iron deficiency, which can lead to anemia, is also associated with ulcerative colitis-related fatigue."

4. Thiopurines, a previously unrecognised cause for fatigue in patients with inflammatory bowel disease

5. https://s3-eu-west-1.amazonaws.com/files.crohnsandcolitis.org.uk/Publications/fatigue-and-IBD.pdf

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